When it comes to protecting our feline friends against parasites, no cat parent would even compromise an ounce of quality. We all want nothing short of the best. But finding ‘the one’ pawfect treatment among various is a hard nut to crack. Therefore, we have prepared a thorough comparison of two popular antiparasitic cat treatments, i.e., Revolution Plus vs Frontline Plus. Read through the blog to select the most suitable treatment for your furry friend.
Revolution Plus & Frontline Plus – Overview
Revolution Plus is a topical formula, recommended for use in kittens and cats from 8 weeks of age and at least 1.25 kg of body weight. This treatment protects felines against heartworm disease, intestinal worms, fleas, ticks and ear mites.
Frontline Plus is an external parasitic treatment, recommended for 8 weeks and older kittens and cats, weighing at least 1 kg. This treatment protects cats against fleas, ticks and chewing lice for one month.
Revolution Plus vs Frontline Plus – Similarities
When it comes to product features, Revolution Plus and Frontline Plus share some similarities and differences. Let’s have a look at their common features first.
Feline age
Both of these treatments are recommended for use in kittens from 8 weeks (2 months) of age.
Fleas, ticks & lice
Revolution Plus and Frontline Plus kill fleas and ticks through contact. Cats don’t need to take a bite from the parasites to kill them. Both of these treatments also kill chewing lice.
Treatment form
Either of these antiparasitics is made in the topical (spot-on) form that should be applied on the cat’s skin.
Durability
Revolution Plus and Frontline Plus both protect cats against a range of parasites for one month.
Revolution Plus & Frontline Plus – Differences
Revolution Plus and Frontline Plus have quite a few differences. Take a look at how they differ from each other.
Composition
Revolution Plus contains selamectin and sarolaner as its active ingredients. Frontline Plus is composed of fipronil and s-methoprene.
Feline weight
The minimum recommended cat weight for the use of Revolution Plus is 1.25kg, whereas it is 1 kg for Frontline Plus.
Heartworm & Intestinal worm protection
Revolution Plus prevents heartworm disease and eliminates intestinal worms including roundworms and hookworms. Frontline Plus does not protect against heartworms or intestinal worms.
Protection against ear mites
Revolution Plus protects against ear mites. Frontline Plus is not known to be effective against ear mites.
Revolution Plus vs Frontline Plus – Comparison Table
The table below displays a thorough comparison of Revolution Plus and Frontline Plus product features.

Frontline Plus & Revolution Plus : Summary
All things considered, Revolution Plus and Frontline Plus both are vet-recommended, highly effective antiparasitic treatments for cats.
When it comes to protecting cats against fleas, ticks and lice, both Revolution Plus and Frontline Plus will do the job for you (considering your feline is at least 1.25 kg in body weight). If you want additional protection against heartworms, intestinal worms and ear mites, go for Revolution Plus.
Regardless of the treatment you choose to use on your feline friend, consulting a veterinarian beforehand will always favour the cat.